Ivo Vranesic

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

Biochemistry, Functional Selectivity, Medicine +7

CPCCOEt, a Noncompetitive Metabotropic Glutamate Receptor 1 Antagonist, Inhibits Receptor Signaling Without Affecting Glutamate Binding

Stephane Litschig, F. Gasparini, D Rueegg et al. · Molecular Pharmacology · 1999 · 342 citations

The Non-competitive Antagonists 2-Methyl-6-(phenylethynyl)pyridine and 7-Hydroxyiminocyclopropan[b]chromen-1a-carboxylic Acid Ethyl Ester Interact with Overlapping Binding Pockets in the Transmembrane Region of Group I Metabotropic Glutamate Receptors

Adriana Pagano, Doris Rüegg, Stephane Litschig et al. · Journal of Biological Chemistry · 2000 · 267 citations · Full text

Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function

Katherine Walker, M. Bowes, Moh Panesar et al. · Neuropharmacology · 2001 · 165 citations

Pain Medicine, Medicine, Neuropathic Pain +7

Responses to Metabotropic Glutamate Receptor Activation in Cerebellar Purkinje Cells: Induction of an Inward Current

C. Staub, Ivo Vranesic, Thomas Knöpfel · European Journal of Neuroscience · 1992 · 153 citations

Cerebellar Purkinje Cells, Synaptic Transmission, Neurotransmitter +19