Nicolas Sprynski

Discovery of a Novel Metallo-β-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae

Martin Everett, Nicolas Sprynski, Alicia Coelho et al. · Antimicrobial Agents and Chemotherapy · 2018 · 94 citations · Full text

SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model

Simon Leiris, Alicia Coelho, Jérôme Castandet et al. · ACS Infectious Diseases · 2018 · 53 citations · Full text

Metallo-β-lactamase Inhibitors, Pharmacotherapy, Antimicrobial Chemotherapy +25

ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing <i>Enterobacteriaceae</i>

David T. Davies, Simon Leiris, Nicolas Sprynski et al. · ACS Infectious Diseases · 2020 · 43 citations

Potent Ndm Inhibitor, Microbial Pathogens, Antimicrobial Chemotherapy +24

Pseudomonas aeruginosa Elastase Contributes to the Establishment of Chronic Lung Colonization and Modulates the Immune Response in a Murine Model

Cristina Cigana, Jérôme Castandet, Nicolas Sprynski et al. · Frontiers in Microbiology · 2021 · 41 citations · Full text

Novel Specific Metallo-β-Lactamase Inhibitor ANT2681 Restores Meropenem Activity to Clinically Effective Levels against NDM-Positive <i>Enterobacterales</i>

Magdalena Zalacaín, Clarisse Lozano, Agustina Llanos et al. · Antimicrobial Agents and Chemotherapy · 2021 · 35 citations · Full text