Katja Valjavec

Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα

Kaja Bergant, Matej Janežič, Katja Valjavec et al. · European Journal of Medicinal Chemistry · 2019 · 26 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +7

Dynophore-Based Approach in Virtual Screening: A Case of Human DNA Topoisomerase IIα

Matej Janežič, Katja Valjavec, Kaja Bergant Loboda et al. · International Journal of Molecular Sciences · 2021 · 21 citations · Full text

Drug Target, Dna Analysis, Molecular Biology +28

Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα

Kaja Bergant Loboda, Katja Valjavec, Martina Štampar et al. · Bioorganic Chemistry · 2020 · 19 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +9

Catalytic Mechanism of ATP Hydrolysis in the ATPase Domain of Human DNA Topoisomerase IIα

Mitja Ogrizek, Matej Janežič, Katja Valjavec et al. · Journal of Chemical Information and Modeling · 2022 · 18 citations · Full text

Atpase Domain, Engineering, Molecular Biology +18

Design, Synthesis and Evaluation of Fused Bicyclo[2.2.2]octene as a Potential Core Scaffold for the Non-Covalent Inhibitors of SARS-CoV-2 3CLpro Main Protease

Barbara Herlah, Andrej Hoivik, Luka Jamšek et al. · Pharmaceuticals · 2022 · 11 citations · Full text