Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Evan W. Weber, Kevin R. Parker, Elena Sotillo, +23

Science

Resetting Epigenetic Memory by Reprogramming of Histone Modifications in Mammals

Hui Zheng, Bo Huang, Bingjie Zhang, +9

Molecular Cell

Molecular and Genetic Evidence for the Key Role of AtCaM3 in Heat-Shock Signal Transduction in Arabidopsis    

Wei Zhang, Ren‐Gang Zhou, Yingjie Gao, +4

PLANT PHYSIOLOGY

Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial

Mitzi M. Gonzales, Valentina R. Garbarino, Tiffany F. Kautz, +17

Nature Medicine

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineClinical TrialsVascular Dementia +10

Enhanced safety and efficacy of protease-regulated CAR-T cell receptors

Louai Labanieh, Robbie G. Majzner, Dorota D. Klysz, +19

Cell

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence

Insup Choi, Minghui Wang, Seungyeul Yoo, +8

Nature Cell Biology

Cell AutophagyAlzheimer's DiseasePrevents Microglial SenescenceAmyloid PlaquesMedicine +9

Adipose Subtype-Selective Recruitment of TLE3 or Prdm16 by PPARγ Specifies Lipid Storage versus Thermogenic Gene Programs

Claudio J. Villanueva, Laurent Vergnes, Jiexin Wang, +13

Cell Metabolism

Metabolic SyndromeTranscriptional RegulationGeneticsMetabolic RegulationLipid Science +7

Intron-Mediated Alternative Splicing of WOOD-ASSOCIATED NAC TRANSCRIPTION FACTOR1B Regulates Cell Wall Thickening during Fiber Development in <i>Populus</i> Species 

Yunjun Zhao, Jiayan Sun, Peng Xu, +2

PLANT PHYSIOLOGY

Inosine induces stemness features in CAR-T cells and enhances potency

Dorota D. Klysz, Carley Fowler, Meena Malipatlolla, +24

Cancer Cell

Application of self-organizing competitive neural network in fault diagnosis of suck rod pumping system

Peng Xu, Shijin Xu, Hongwei Yin

Journal of Petroleum Science and Engineering

Fault DiagnosisEngineeringDiagnosisFault ForecastingSystems Engineering +3