Holly A. Byers

Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting

Jerry Li, Nicholas Purser, Joanna Liwocha et al. · Molecular Cell · 2024 · 42 citations · Full text

Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration

Amy Northrop, Holly A. Byers, Senthil K. Radhakrishnan · Molecular Biology of the Cell · 2020 · 39 citations · Full text

Proteasome, Molecular Biology, Cell Death +19

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Madison A. Ward, Janakiram R. Vangala, Hatem Elif Kamber Kaya et al. · The Journal of Cell Biology · 2024 · 14 citations · Full text

Proteasome Inhibition, Transcriptional Regulation, Cell Autophagy +13

Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs

David C. Boyd, Emily K. Zboril, Amy L. Olex et al. · Cancers · 2023 · 13 citations · Full text

Combinatorial Chemistry, Gene Amplification, Breast Oncology +20

Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer

Holly A. Byers, Amy N. Brooks, Janakiram R. Vangala et al. · Scientific Reports · 2023 · 13 citations · Full text