Concepedia

Nicholas Purser

NP

5

Publications

166

Citations

5

H-Index

2020

Active since

Affiliations

Max Planck Institute of Biochemistry(Current)

University of Nevada, Las Vegas

St. Jude Children's Research Hospital

Howard Hughes Medical Institute

Harvard University

Nicholas Purser is an author at Max Planck Institute of Biochemistry specializing in natural sciences, molecular biology, and medicine.

Top concepts

MedicineNatural SciencesMolecular BiologyBiochemistryCell SignalingProtein FoldingChemical BiologyProtein AssemblyStructural BiologySignal Transduction

Publications per year

2020–2024

5

Publications

5

Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting

Jerry Li, Nicholas Purser, Joanna Liwocha et al. · Molecular Cell · 2024 · 42 citations · Full text

Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases

Joanna Liwocha, Jerry Li, Nicholas Purser et al. · Nature Structural & Molecular Biology · 2024 · 40 citations · Full text

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

Joanna Liwocha, David T. Krist, Gerbrand J. van der Heden van Noort et al. · Nature Chemical Biology · 2020 · 38 citations · Full text

Protein Chemistry, Protein Assembly, Biochemistry +9

E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity

Daniel C. Scott, Moeko T. King, Kheewoong Baek et al. · Molecular Cell · 2023 · 36 citations · Full text

Protein Function, Signal Transduction, Molecular Regulation +8

Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases

Daniel C. Scott, Sagar Chittori, Nicholas Purser et al. · Nature Communications · 2024 · 10 citations · Full text

Rows per page

1–5 of 5