Presenilin-1 and -2 Are Molecular Targets for γ-Secretase Inhibitors

Dietmar Seiffert, Jodi D. Bradley, Cynthia M. Rominger, +18

Journal of Biological Chemistry

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

Michael W. Pantoliano, Robert A. Horlick, Barry A. Springer, +7

Biochemistry

Cooperative Growth FactorGlycobiologyAnalytical UltracentrifugationCell GrowthChemical Biology +23

Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells

Phillip C.C. Liu, Xiangdong Liu, Yanlong Li, +31

Cancer Biology & Therapy

Erbb Family MembersBreast OncologyMolecular BiologyMajor SourceMolecular Research +17

High-level expression and purification of secreted forms of herpes simplex virus type 1 glycoprotein gD synthesized by baculovirus-infected insect cells

William P. Sisk, Jodi D. Bradley, Robert J. Leipold, +6

Journal of Virology

Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus.

Jodi D. Bradley, Yuki Kataoka, Sunil J. Advani, +7

PubMed

Radiation EffectImmunologyRadiation ExposureHigh-grade GliomasRadiation Biology +17

Expression and processing of biologically active fibroblast growth factors in the yeast Saccharomyces cerevisiae.

P J Barr, Lawrence S. Cousens, Chun Ting Lee-Ng, +7

Journal of Biological Chemistry

Human FgfsEngineeringHuman GrowthCell ProliferationCell Growth +20

Evidence that thrombocytopenia observed in humans treated with orally bioavailable glycoprotein IIb/IIIa antagonists is immune mediated

Jeffrey T. Billheimer, Ira B. Dicker, Richard Wynn, +15

Blood

Differential effects of heparin, fibronectin, and laminin on the phosphorylation of basic fibroblast growth factor by protein kinase C and the catalytic subunit of protein kinase A.

Jean‐Jacques Feige, Jodi D. Bradley, K Fryburg, +4

The Journal of Cell Biology

PathologyCell ProliferationCytoskeletonCell GrowthBasic Fgf +22

Mutations at the P1′ position of Notch1 decrease intracellular domain stability rather than cleavage by γ-secretase

Yuval Blat, Jere E. Meredith, Qian Wang, +5

Biochemical and Biophysical Research Communications

Protein FunctionSignal TransductionNotch1 Decrease IntracellularMolecular RegulationNatural Sciences +7

Deletion of hydrophobic domains of viral glycoproteins increases the level of their production in Escherichia coli

William P. Sisk, Jodi D. Bradley, David M. Kingsley, +1

Gene

Viral GlycoproteinsVirus StructureProtein FoldingNatural SciencesVirulence Factor +10