Nirvana A. Gohar

In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies

Eman A. Fayed, Yousry A. Ammar, Ahmed Ragab et al. · Bioorganic Chemistry · 2020 · 53 citations

Pharmaceutical Science, Pharmacological Study, Pharmacology +10

Development of new spiro[1,3]dithiine-4,11′-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation

Ahmed Ragab, Moustafa S. Abusaif, Nirvana A. Gohar et al. · Bioorganic Chemistry · 2022 · 53 citations

Medicinal Chemistry, Biochemistry, New Spiro +9

Design, synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents

Eman A. Fayed, Sally I. Eissa, Ashraf H. Bayoumi et al. · Molecular Diversity · 2018 · 43 citations

Combinatorial Chemistry, Medicinal Chemistry, Engineering +12

Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting <i>α</i> -amylase, and <i>α</i> -glucosidase: synthesis, molecular docking, and ADMET studies

Nirvana A. Gohar, Eman A. Fayed, Yousry A. Ammar et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2024 · 35 citations · Full text

Upregulation of BAX and caspase‐3, as well as downregulation of Bcl‐2 during treatment with indeno[1,2‐<i>b</i>]quinoxalin derivatives, mediated apoptosis in human cancer cells

Eman A. Fayed, Nirvana A. Gohar, Amel M. Farrag et al. · Archiv der Pharmazie · 2022 · 28 citations