Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

Ellis Chika Onwordi, Els F. Halff, Thomas Whitehurst, +13

Nature Communications

Two Binding Sites for [³H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation

David R. Owen, Owain W. Howell, Sac-Pham Tang, +9

Journal of Cerebral Blood Flow & Metabolism

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans

David R. Owen, Nehal Narayan, Lisa Wells, +13

Journal of Cerebral Blood Flow & Metabolism

Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine

Michelle Kokkinou, Elaine E. Irvine, David R. Bonsall, +13

Molecular Psychiatry

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer’s disease patients and control subjects

Andrea Varrone, Vesa Oikonen, Anton Forsberg, +20

European Journal of Nuclear Medicine and Molecular Imaging

Positron Emission TomographyNeuroimaging BiomarkersNeurodegenerative DiseasesAlzheimer's DiseaseNeuroimaging +7

The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory ‘M1’ human macrophages

Nehal Narayan, Harpreet Mandhair, Erica Smyth, +6

PLoS ONE

Translocator ProteinImmunologyImmune RegulationPathologyInnate Immunity +23

Translocator Protein as an Imaging Marker of Macrophage and Stromal Activation in Rheumatoid Arthritis Pannus

Nehal Narayan, David R. Owen, Harpreet Mandhair, +9

Journal of Nuclear Medicine

Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery

Vadim Bernard‐Gauthier, Andrew V. Mossine, Ashley C. Knight, +24

Journal of Medicinal Chemistry

Imaging of Chemotherapy-Induced Acute Cardiotoxicity with ¹⁸F-Labeled Lipophilic Cations

Stuart P. McCluskey, Anna Haslop, Christopher Coello, +6

Journal of Nuclear Medicine

EngineeringOncologic ImagingImaging AgentCardiovascular PharmacologyCardiac Retention +17

DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats

Puneet Sharma, Lisa Wells, Gaia Rizzo, +6

Neurotherapeutics