Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Marie A.C. Depuydt, Koen H.M. Prange, Lotte Slenders, +20

Circulation Research

T cell fate and clonality inference from single-cell transcriptomes

Michael J. T. Stubbington, Tapio Lönnberg, Valentina Proserpio, +4

Nature Methods

Cell LineageSingle Cell SequencingMedicineT Cell FateSingle-cell Genomics +4

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves T _H 1/T _FH fate bifurcation in malaria

Tapio Lönnberg, Valentine Svensson, Kylie R. James, +20

Science Immunology

Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils

Akira Takeda, Maija Hollmén, Denis Đermadi, +11

Immunity

Endothelial Cell PathobiologyInflammationGranulocyteImmunologyBlood Cell +7

Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci

Tiit Örd, Kadri Õunap, Lindsey K. Stolze, +10

Circulation Research

Visual LanguageSingle Cell SequencingMedicineGeneticsGraphic Design +10

Global Chromatin State Analysis Reveals Lineage-Specific Enhancers during the Initiation of Human T helper 1 and T helper 2 Cell Polarization

R. David Hawkins, Antti Larjo, Subhash Tripathi, +9

Immunity

ChromatinChromatin StructureHuman TChromatin RemodelingNatural Sciences +11

Single-cell characterization of anti–LAG-3 and anti–PD-1 combination treatment in patients with melanoma

Jani Huuhtanen, Henna H.E. Kasanen, Katriina Peltola, +17

Journal of Clinical Investigation

ImmunologyNk CellsImmunoeditingSingle-cell CharacterizationImmune Cell Therapy +17

Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory

Megan S. F. Soon, Hyun Jae Lee, Jessica A. Engel, +23

Nature Immunology

Transcriptome DynamicsT-regulatory CellMalariaImmunologyImmunodominance +6

Early Detection of Peripheral Blood Cell Signature in Children Developing β-Cell Autoimmunity at a Young Age

Henna Kallionpää, Juhi Somani, Soile Tuomela, +18

Diabetes

Quantitative Proteomics Analysis of the Nuclear Fraction of Human CD4+ Cells in the Early Phases of IL-4-induced Th2 Differentiation

Robert Moulder, Tapio Lönnberg, Laura L. Elo, +7

Molecular & Cellular Proteomics

Laboratory ImmunologyTh2 Cell DifferentiationImmunologyCd4 T Cell ResponsesImmunotherapy +16