Tiina Leino

Genetic Alteration of α2C-Adrenoceptor Expression in Mice: Influence on Locomotor, Hypothermic, and Neurochemical Effects of Dexmedetomidine, a Subtype-Nonselective α2-Adrenoceptor Agonist

Jukka Sallinen, Richard E. Link, Antti Haapalinna et al. · Molecular Pharmacology · 1997 · 172 citations

Medicine, Genetics, Pharmacology +13

Alkyl-substituted silica gel as a carrier in the controlled release of dexmedetomidine

Pirjo Kortesuo, Manja Ahola, Minna Kangas et al. · Journal of Controlled Release · 2001 · 86 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Effect of synthesis parameters of the sol–gel-processed spray-dried silica gel microparticles on the release rate of dexmedetomidine

Pirjo Kortesuo, Manja Ahola, Minna Kangas et al. · Biomaterials · 2002 · 62 citations

Pharmacy, Pharmaceutics, Pharmacology +14

The ?2-adrenoceptor antagonist atipamezole potentiates anti-Parkinsonian effects and can reduce the adverse cardiovascular effects of dopaminergic drugs in rats

Antti Haapalinna, Tiina Leino, Esa Heinonen · Naunyn-Schmiedeberg s Archives of Pharmacology · 2003 · 34 citations

Medicine, Neuroscience, Pharmacology +11

In vitro and in vivo profiling of fadolmidine, a novel potent α2-adrenoceptor agonist with local mode of action

Jyrki Lehtimäki, Tiina Leino, Ari Koivisto et al. · European Journal of Pharmacology · 2008 · 24 citations

Medicine, Medicinal Chemistry, Pharmacology +10