Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

Alison E. Ringel, Jefte M. Drijvers, Gregory J. Baker, +19

Cell

ObesityCancer ImmunosurveillanceImmunologyTumor ImmunityBiological Microenvironments +6

Transcellular Diapedesis Is Initiated by Invasive Podosomes

Christopher V. Carman, Peter T. Sage, Tracey Sciuto, +6

Immunity

Transcellular Diapedesis IsCell TraffickingExtracellular MicrovesiclesCytoskeletonIntracellular Trafficking +4

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

Peter T. Sage, Loise M. Francisco, Christopher V. Carman, +1

Nature Immunology

Autoimmune DiseaseMedicineT-regulatory CellImmunologyImmune Regulation +9

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability

Alexandria Huynh, Michel DuPage, Bhavana Priyadharshini, +9

Nature Immunology

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation

Noga Ron‐Harel, Daniel Santos, Jonathan M. Ghergurovich, +11

Cell Metabolism

T Cell ActivationMitochondrial BiogenesisMitochondrial FunctionMetabolismMetabolic Remodeling +5

The Coinhibitory Receptor CTLA-4 Controls B Cell Responses by Modulating T Follicular Helper, T Follicular Regulatory, and T Regulatory Cells

Peter T. Sage, Alison M. Paterson, Scott B. Lovitch, +1

Immunity

Signal TransductionAutoimmune DiseaseAdaptive Immune SystemImmune Cell DevelopmentT Follicular Regulatory +13

Circulating T follicular regulatory and helper cells have memory-like properties

Peter T. Sage, David Álvarez, Jernej Godec, +2

Journal of Clinical Investigation

Adaptive Immune SystemT-regulatory CellImmunologyImmune RegulationSocial Sciences +15

Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade

Zachary A. Cooper, Vikram R. Juneja, Peter T. Sage, +12

Cancer Immunology Research

ImmunologyImmune RegulationImmunoeditingMelanoma Is EnhancedCd4 T Cell Responses +22

Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses

Rachel L. Clement, Joe Daccache, Mostafa T. Mohammed, +6

Nature Immunology

InflammationAllergyAutoimmune DiseaseAllergic ImmunityAdaptive Immune System +12

PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

Catherine L. Tan, Juhi R. Kuchroo, Peter T. Sage, +15

The Journal of Experimental Medicine