David Dukhan

Antiviral <scp>l</scp> -Nucleosides Specific for Hepatitis B Virus Infection

Martin L. Bryant, Edward G. Bridges, L Placidi et al. · Antimicrobial Agents and Chemotherapy · 2001 · 179 citations · Full text

Pharmacology of β- <scp>l</scp> -Thymidine and β- <scp>l</scp> -2′-Deoxycytidine in HepG2 Cells and Primary Human Hepatocytes: Relevance to Chemotherapeutic Efficacy against Hepatitis B Virus

Brenda I. Hernández-Santiago, L Placidi, E. Cretton‐Scott et al. · Antimicrobial Agents and Chemotherapy · 2002 · 52 citations · Full text

Synthesis, Conformational Analysis, and Biological Activity of<i>C</i>-Thioribonucleosides Related to Tiazofurin

Palmarisa Franchetti, Stefano Marchetti, Loredana Cappellacci et al. · Journal of Medicinal Chemistry · 2000 · 40 citations

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

François-René Alexandre, Eric Badaroux, John P. Bilello et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 32 citations · Full text

Medicine, Antiviral Drug Development, Antiviral Therapy +9

How S–C–N anomeric effects and energetic preference across [S–C–C–O] fragments steer conformational equilibria in 4′-thionucleosides. 1H NMR and ab initio MO study †

Martin Črnugelj, David Dukhan, Jean‐Louis Barascut et al. · Journal of the Chemical Society Perkin Transactions 2 · 2000 · 20 citations

Nucleic Acid Chemistry, Biochemistry, S–c–n Anomeric Effects +13