Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome

Fiorenza Stagni, Andrea Giacomini, Marco Emili, +6

Neuroscience

Down SyndromeDevelopmental BiologyTs65dn Mouse ModelBrain DevelopmentMedicine +9

A flavonoid agonist of the TrkB receptor for BDNF improves hippocampal neurogenesis and hippocampus-dependent memory in the Ts65Dn mouse model of DS

Fiorenza Stagni, Andrea Giacomini, Sandra Guidi, +7

Experimental Neurology

Hippocampal NeurogenesisTs65dn Mouse ModelMedicineTrkb ReceptorNeuropharmacology +6

Abnormal development of the inferior temporal region in fetuses with Down syndrome

Sandra Guidi, Andrea Giacomini, Fiorenza Stagni, +4

Brain Pathology

Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome

Andrea Giacomini, Fiorenza Stagni, Stefania Trazzi, +5

Neurobiology of Disease

Ts65dn Mouse ModelGeneticsNeurogenesis ImpairmentAmyloid Precursor ProteinSynaptic Signaling +15

Neuroanatomical alterations in higher-order thalamic nuclei of fetuses with Down syndrome

Fiorenza Stagni, Andrea Giacomini, Marco Emili, +4

Clinical Neurology and Neurosurgery

Down SyndromeDevelopmental BiologyNeuroanatomical AlterationsNeuroanatomyNeuroscience +6

Subicular hypotrophy in fetuses with Down syndrome and in the Ts65Dn model of Down syndrome

Fiorenza Stagni, Andrea Giacomini, Marco Emili, +4

Brain Pathology

Treatment with corn oil improves neurogenesis and cognitive performance in the Ts65Dn mouse model of Down syndrome

Andrea Giacomini, Fiorenza Stagni, Marco Emili, +6

Brain Research Bulletin

Down SyndromeNeuroregenerationMolecular NeuroscienceDevelopmental BiologyTs65dn Mouse Model +10

Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone

Daniela Valenti, Fiorenza Stagni, Marco Emili, +3

Antioxidants

Ts65dn Mouse ModelBrain DevelopmentMitochondrial DysfunctionSynaptic SignalingSocial Sciences +20

Epigallocatechin gallate: A useful therapy for cognitive disability in Down syndrome?

Fiorenza Stagni, Andrea Giacomini, Marco Emili, +3

Neurogenesis

Neuroanatomical alterations and synaptic plasticity impairment in the perirhinal cortex of the Ts65Dn mouse model of Down syndrome

Vincenzo Roncacè, Costanza Burattini, Fiorenza Stagni, +5

Neurobiology of Disease

Down SyndromeSynaptic PlasticityDevelopmental BiologyTs65dn Mouse ModelNeurophysiology +11