Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

Ben Killingley, Alex Mann, Mariya Kalinova, +27

Nature Medicine

Young AdultsViral PersistenceViral KineticsCovid-19 PandemicImmunology +4

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice

Paméla Gasse, Caroline Mary, Isabelle Guénon, +9

Journal of Clinical Investigation

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent

Emilie Doz, Nicolas Noulin, Elisabeth Boichot, +8

The Journal of Immunology

Dual Effects of p38 MAPK on TNF-Dependent Bronchoconstriction and TNF-Independent Neutrophil Recruitment in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome

Silvia Schnyder‐Candrian, Valérie Quesniaux, Franco Di Padova, +8

The Journal of Immunology

Acute Lung InjuryInflammatory Lung DiseaseTnf-independent Neutrophil RecruitmentLung InflammationImmunology +16

Both Hemopoietic and Resident Cells Are Required for MyD88-Dependent Pulmonary Inflammatory Response to Inhaled Endotoxin

Nicolas Noulin, Valérie Quesniaux, Silvia Schnyder‐Candrian, +6

The Journal of Immunology

Prevention of Respiratory Syncytial Virus Infection in Healthy Adults by a Single Immunization of Ad26.RSV.preF in a Human Challenge Study

Jerald Sadoff, Els De Paepe, John P. DeVincenzo, +14

The Journal of Infectious Diseases

Enhancement of Methacholine-Evoked Tracheal Contraction Induced by Bacterial Lipopolysaccharides Depends on Epithelium and Tumor Necrosis Factor

Thomas Sécher, Fernando Rodrigues Coelho, Nicolas Noulin, +11

Journal of Allergy

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge

Ben Killingley, Alex Mann, Mariya Kalinova, +27

VaccinationLong CovidViral KineticsWild-type VirusEmerging Infectious Diseases +11

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin

Laure Janot, Jean‐Claude Sirard, Thomas Sécher, +8

European Journal of Immunology

Radioresistant CellsInflammatory Lung DiseaseLung InflammationInnate Immune SystemImmunology +19

Intranasal H5N1 Vaccines, Adjuvanted with Chitosan Derivatives, Protect Ferrets against Highly Pathogenic Influenza Intranasal and Intratracheal Challenge

Alex Mann, Nicolas Noulin, Andrew Catchpole, +13

PLoS ONE

VaccinationChitosan DerivativesCross-protectionMucosal VaccinationVeterinary Vaccine +13