Jessica Kalra

QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model

Jessica Kalra, Corinna Warburton, Karen Fang et al. · Breast Cancer Research · 2009 · 74 citations · Full text

Medicine, Oncology, Pharmacology +17

5′-AMP-activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experimental Human Breast Cancer Tumors

Keith R. Laderoute, Joy M. Calaoagan, Wan‐Ru Chao et al. · Journal of Biological Chemistry · 2014 · 70 citations · Full text

Medicine, Cancer Biology, Oncology +10

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of Integrin-linked kinase (ILK)

Lincoln Edwards, Janet Woo, Lynsey A. Huxham et al. · Molecular Cancer Therapeutics · 2008 · 62 citations

Medicine, Cancer Biology, Pharmacology +17

Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism

Jessica Kalra, Qing Shao, Hong Qin et al. · Carcinogenesis · 2006 · 60 citations

Life Sciences, Cell Biology, Oncology +15

Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1

Jessica Kalra, Brent W. Sutherland, Anna L. Stratford et al. · Oncogene · 2010 · 50 citations · Full text

Life Sciences, Molecular Biology, Oncology +14