Pau Muñoz‐Guardiola

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

Pau Muñoz‐Guardiola, Josefina Casas, Elisabet Megías‐Roda et al. · Autophagy · 2020 · 113 citations · Full text

Life Sciences, Oncology, Pharmacology +17

The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase

Tatiana Erazo, Mar Lorente, Anna López‐Plana et al. · Clinical Cancer Research · 2015 · 74 citations · Full text

Medicine, Oncology, Pharmacology +17

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

Jinhua Wang, Tatiana Erazo, Fleur M. Ferguson et al. · ACS Chemical Biology · 2018 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer

Isidre Felip, Cristian P. Moiola, Cristina Megino‐Luque et al. · Gynecologic Oncology · 2019 · 39 citations

Life Sciences, Cell Biology, Oncology +16

The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer

Anna López‐Plana, Patricia Fernández‐Nogueira, Pau Muñoz‐Guardiola et al. · International Journal of Cancer · 2020 · 24 citations · Full text

Medicine, Oncology, Pharmacology +17