ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Jer-Yen Yang, Cong S. Zong, Weiya Xia, +23

Nature Cell Biology

Mdm2-mediated DegradationMedicineTumor SuppressorOncologyCell Biology +2

IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway

Dung‐Fang Lee, Hsu-Ping Kuo, Chun‐Te Chen, +18

Cell

InflammationSignal TransductionSignaling PathwayCell RegulationMedicine +8

Erk Associates with and Primes GSK-3β for Its Inactivation Resulting in Upregulation of β-Catenin

Qingqing Ding, Weiya Xia, Jaw-Ching Liu, +13

Molecular Cell

Signal TransductionSignaling PathwayCell RegulationMolecular RegulationErk Associates +8

Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds

Cheng‐Wen Lin, Fuu‐Jen Tsai, Chang‐Hai Tsai, +5

Antiviral Research

Isatis Indigotica RootMedicineAntiviral Drug DevelopmentVirologyPhytochemical +6

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

Yongkun Wei, Ya-Huey Chen, Long‐Yuan Li, +8

Nature Cell Biology

Regenerative MedicineCdk1-dependent PhosphorylationDevelopmental BiologyMedicineStem Cell Research +6

KEAP1 E3 Ligase-Mediated Downregulation of NF-κB Signaling by Targeting IKKβ

Dung‐Fang Lee, Hsu-Ping Kuo, Mo Liu, +16

Molecular Cell

InflammationTranscriptional RegulationSignal TransductionSignaling PathwayMolecular Pathway +9

The Crosstalk of mTOR/S6K1 and Hedgehog Pathways

Yan Wang, Qingqing Ding, Chia-Jui Yen, +24

Cancer Cell

Signal TransductionHedgehog PathwaysCell DivisionSignaling PathwayIntercellular Communication +4

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation

Jung-Mao Hsu, Chun‐Te Chen, Chao‐Kai Chou, +12

Nature Cell Biology

Signal TransductionSignaling PathwayTyr 1173Cell RegulationMedicine +8

SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies

Ya‐Chen Liang, Chia-Chin Lee, Yali Yao, +3

Scientific Reports

Down-regulation of Myeloid Cell Leukemia-1 through Inhibiting Erk/Pin 1 Pathway by Sorafenib Facilitates Chemosensitization in Breast Cancer

Qingqing Ding, Longfei Huo, Jer-Yen Yang, +16

Cancer Research