Chien‐Chen Lai

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Jer-Yen Yang, Cong S. Zong, Weiya Xia et al. · Nature Cell Biology · 2008 · 693 citations · Full text

Mdm2-mediated Degradation, Medicine, Tumor Suppressor +4

IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway

Dung‐Fang Lee, Hsu-Ping Kuo, Chun‐Te Chen et al. · Cell · 2007 · 625 citations · Full text

Inflammation, Signal Transduction, Signaling Pathway +10

Erk Associates with and Primes GSK-3β for Its Inactivation Resulting in Upregulation of β-Catenin

Qingqing Ding, Weiya Xia, Jaw-Ching Liu et al. · Molecular Cell · 2005 · 592 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +10

Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds

Cheng‐Wen Lin, Fuu‐Jen Tsai, Chang‐Hai Tsai et al. · Antiviral Research · 2005 · 543 citations

Isatis Indigotica Root, Medicine, Antiviral Drug Development +8

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

Yongkun Wei, Ya-Huey Chen, Long‐Yuan Li et al. · Nature Cell Biology · 2010 · 392 citations

Regenerative Medicine, Cdk1-dependent Phosphorylation, Developmental Biology +8