Lisanne Noordam

Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance

Jiaye Liu, Pengfei Li, Ling Wang et al. · Cellular and Molecular Gastroenterology and Hepatology · 2020 · 191 citations · Full text

Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules

Guoying Zhou, Dave Sprengers, Shanta Mancham et al. · Journal of Hepatology · 2019 · 123 citations

Ex Vivo, Immune Checkpoint Molecules, Cancer Immunosurveillance +12

An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity

Yuanming Xu, Lucia Campos Carrascosa, Yik A. Yeung et al. · Cancer Immunology Research · 2021 · 95 citations · Full text

LGR5 marks targetable tumor-initiating cells in mouse liver cancer

Wanlu Cao, Meng Li, Jiaye Liu et al. · Nature Communications · 2020 · 90 citations · Full text

TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma

Zhouhong Ge, Guoying Zhou, Lucia Campos Carrascosa et al. · Cellular and Molecular Gastroenterology and Hepatology · 2021 · 81 citations · Full text