Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

Guoying Zhou, Dave Sprengers, Patrick P.C. Boor, +13

Gastroenterology

Cancer ImmunosurveillanceT-regulatory CellImmunologyTumor ImmunityPathology +10

PD-L1, Galectin-9 and CD8⁺ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma

Kostandinos Sideras, Katharina Biermann, Joanne Verheij, +17

OncoImmunology

Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules

Guoying Zhou, Dave Sprengers, Shanta Mancham, +17

Journal of Hepatology

Ex VivoImmune Checkpoint MoleculesCancer ImmunosurveillanceMedicineBiliary Cancer +10

Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors

Alexander Pedroza‐González, Guoying Zhou, Ernesto Vargas-Méndez, +13

OncoImmunology

Liver Grafts Contain a Unique Subset of Natural Killer Cells That Are Transferred Into the Recipient After Liver Transplantation

Viviana Moroso, Herold J. Metselaar, Shanta Mancham, +7

Liver Transplantation

Counter-regulation of rejection activity against human liver grafts by donor PD-L1 and recipient PD-1 interaction

Xiaolei Shi, Shanta Mancham, Bettina E. Hansen, +6

Journal of Hepatology

Transplant RejectionXenotransplantationTransplantationHepatologyRejection Activity +13

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer

Guoying Zhou, Lisanne Noordam, Dave Sprengers, +14

OncoImmunology

Characterization of human liver dendritic cells in liver grafts and perfusates

Brenda M. Bosma, Herold J. Metselaar, Shanta Mancham, +6

Liver Transplantation

Prednisolone Suppresses the Function and Promotes Apoptosis of Plasmacytoid Dendritic Cells

Patrick P.C. Boor, Herold J. Metselaar, Shanta Mancham, +3

American Journal of Transplantation

InflammationPlasmacytoid Dendritic CellsAnti-inflammatoryAutoimmune DiseaseMedicine +11

Tumor cell expression of immune inhibitory molecules and tumor-infiltrating lymphocyte count predict cancer-specific survival in pancreatic and ampullary cancer

Kostandinos Sideras, Katharina Biermann, Kevin Yi‐Lwern Yap, +9

International Journal of Cancer

ImmunologyImmune RegulationPathologyImmunoeditingImmune Resistance +17