Anja Brehm

Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production

Anja Brehm, Yin Liu, Afzal Sheikh et al. · Journal of Clinical Investigation · 2015 · 330 citations · Full text

Genetics, Immunodeficiencies, Immunology +26

Duplications Involving a Conserved Regulatory Element Downstream of BMP2 Are Associated with Brachydactyly Type A2

Katarina Dathe, Klaus Kjaer, Anja Brehm et al. · The American Journal of Human Genetics · 2009 · 158 citations · Full text

Natural Sciences, Genetics, Bmp2 Are Associated +9

Novel proteasome assembly chaperone mutations in PSMG2/PAC2 cause the autoinflammatory interferonopathy CANDLE/PRAAS4

Adriana A. de Jesus, Anja Brehm, Rachel VanTries et al. · Journal of Allergy and Clinical Immunology · 2019 · 107 citations · Full text

Novel Proteasome, Protein Function, Protein Assembly +12

Copy-Number Variations Involving the IHH Locus Are Associated with Syndactyly and Craniosynostosis

Eva Klopocki, Silke B. Lohan, Francesco Brancati et al. · The American Journal of Human Genetics · 2010 · 105 citations · Full text

Developmental Biology, Genetic Disorder, Copy-number Variations +6

Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN

Petra Seemann, Anja Brehm, Jana König et al. · PLoS Genetics · 2009 · 96 citations · Full text

Sclerostin, Immunology, Bone Repair +17