Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the αβ T-cell receptor

Lori Haughn, Sophie Gratton, Lorraine Caron, +3

Nature

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseTyrosine Kinase P56lckImmunology +7

Highly restricted spread of HIV-1 and multiply infected cells within splenic germinal centers

Sophie Gratton, Rémi Cheynier, Marie-Jeanne Dumaurier, +2

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyViral DynamicSequence DiversificationImmune System +15

Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression.

Michel J. Tremblay, Sylvain Meloche, Sophie Gratton, +2

The EMBO Journal

Antigenic stimulation by BCG vaccine as an in vivo driving force for SIV replication and dissemination

Rémi Cheynier, Sophie Gratton, Matilda Halloran, +3

Nature Medicine

VaccinationSiv ReplicationVaccine DevelopmentMedicineVaccine Target +8

Degradation of CD4 Induced by Human Immunodeficiency Virus Type 1 Vpu Protein: A Predicted Alpha-Helix Structure in the Proximal Cytoplasmic Region of CD4 Contributes to Vpu Sensitivity

Xiaojian Yao, Jacques Friborg, Florent Checroune, +4

Virology

Virus StructureViral ReplicationVpu ProteinHuman RetrovirusImmunology +9

Reversible Blockade of Thymic Output: An Inherent Part of TLR Ligand-Mediated Immune Response

Thomas Démoulins, Ali T. Abdallah, Nadia Kettaf, +5

The Journal of Immunology

Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef

Sophie Gratton, Xiaojian Yao, Sundararajan Venkatesan, +2

The Journal of Immunology

The Magnitude of Thymic Output Is Genetically Determined through Controlled Intrathymic Precursor T Cell Proliferation

Gaël Dulude, Rémi Cheynier, Dominique Gauchat, +4

The Journal of Immunology

LFA-1-mediated antigen-independent T cell adhesion is regulated by CD4 and p56<i>lck</i> tyrosine kinase.

Fabienne Mazerolles, Christiane Barbat, Sylvain Meloche, +7

The Journal of Immunology

lck-Independent Inhibition of T Cell Antigen Response by the HIV gp120

Sophie Gratton, Michael Julius, Rafick‐Pierre Sékaly

The Journal of Immunology