Tom Coleman

Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme

Tom Coleman, Alicia M. Kirk, Rebecca R. Chao et al. · ACS Catalysis · 2021 · 55 citations

Crystal Structure, Engineering, Cytochrome P450 Enzyme +17

Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes

Tom Coleman, Jeanette E. Stok, Matthew N. Podgorski et al. · JBIC Journal of Biological Inorganic Chemistry · 2020 · 45 citations

Aldehyde Dehydrogenase, Cellular Enzymology, Biochemistry +8

Cytochrome P450 CYP199A4 from<i>Rhodopseudomonas palustris</i>Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation

Tom Coleman, Siew Hoon Wong, Matthew N. Podgorski et al. · ACS Catalysis · 2018 · 37 citations

CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives

Tom Coleman, Rebecca R. Chao, John B. Bruning et al. · RSC Advances · 2015 · 36 citations

Engineering, Demethenylation Reactions, Molecular Biology +16

Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions

Matthew N. Podgorski, Tom Coleman, Rebecca R. Chao et al. · Journal of Inorganic Biochemistry · 2019 · 33 citations · Full text

Engineering, Biochemistry, Natural Sciences +7