Resistance to Fas-mediated apoptosis: activation of Caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP

Atsushi Suzuki, Yumi Tsutomi, Kouichi Akahane, +2

Oncogene

InflammationSignal TransductionSignaling PathwayCell RegulationApoptosis +7

Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

Atsushi Suzuki, Takeshi Ito, Hirokazu Kawano, +7

Oncogene

Fas-mediated Cell DeathProcaspase 3/P21Signal TransductionSignaling PathwayCell Regulation +12

Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21

Atsushi Suzuki, Yumi Tsutomi, Masayuki Miura, +1

Oncogene

InflammationMitophagySignal TransductionSignaling PathwayCell Regulation +9

Mitochondrial Regulation of Cell Death: Mitochondria Are Essential for Procaspase 3-p21 Complex Formation To Resist Fas-Mediated Cell Death

Atsushi Suzuki, Yumi Tsutomi, Naoe Yamamoto, +2

Molecular and Cellular Biology

Mdlh CellsFas-mediated Cell DeathMitophagyActinomycin DSignal Transduction +13

Procaspase 3/p21 complex formation to resist Fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A

Atsushi Suzuki, Hirokazu Kawano, Midori Hayashida, +3

Cell Death and Differentiation

Procaspase 3/P21Protein Kinase ASignal TransductionSignaling PathwayCell Regulation +12

Levofloxacin, an Optical Isomer of Ofloxacin, Has Attenuated Epileptogenic Activity in Mice and Inhibitory Potency in GABA Receptor Binding

Kouichi Akahane, Yumi Tsutomi, Yasuharu Kimura, +1

Chemotherapy

Inhibitory Activity of Camptothecin Derivatives Against Acetylcholinesterase in Dogs and Their Binding Activity to Acetylcholine Receptors in Rats

Yasuyoshi Kawato, Masayasu Sekiguchi, Kouichi Akahane, +6

Journal of Pharmacy and Pharmacology

Bcl-2 accelerates the neuronal differentiation: new evidence approaching to the biofunction of Bcl-2 in the neuronal system

Atsushi Suzuki, Yumi Tsutomi

Brain Research

Developmental BiologyMolecular NeuroscienceNeurophysiologyNeurological FunctionNew Evidence +12

Possible intermolecular interaction between quinolones and biphenylacetic acid inhibits gamma-aminobutyric acid receptor sites

K Akahane, Yasuharu Kimura, Yumi Tsutomi, +1

Antimicrobial Agents and Chemotherapy

PharmacotherapyDrug ResistanceMedicinal ChemistryBiphenylacetic AcidPossible Intermolecular Interaction +15

Quantitation of GABA_A receptor inhibition required for quinolone-induced convulsions in mice

Yumi Tsutomi, K. Matsubayashi, K Akabane

Journal of Antimicrobial Chemotherapy

NeurotransmitterPharmacotherapyNeurotransmissionExperimental PharmacologySocial Sciences +16