Eva Hilgenfeld

Jumping translocations are common in solid tumor cell lines and result in recurrent fusions of whole chromosome arms

Hesed Padilla‐Nash, Kerstin Heselmeyer‐Haddad, Danny Wangsa et al. · Genes Chromosomes and Cancer · 2001 · 88 citations

Life Sciences, Genetics, Oncology +16

Reciprocal DNA topoisomerase II cleavage events at 5′-TATTA-3′ sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing

Ryan J. Whitmarsh, Charles Saginario, Ya Zhuo et al. · Oncogene · 2003 · 62 citations

Life Sciences, Genetics, Molecular Biology +8

MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site

Diana J. Slater, Eva Hilgenfeld, Eric Rappaport et al. · Oncogene · 2002 · 55 citations

Life Sciences, Genetics, Molecular Genetics +17

Spectral karyotyping and fluorescence <i>in situ</i> hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the <i>MYC</i> oncogene in acute myeloid leukaemia M2

Eva Hilgenfeld, Hesed Padilla‐Nash, Nicole E. McNeil et al. · British Journal of Haematology · 2001 · 44 citations · Full text

Life Sciences, Genetics, Hematology +17

Transforming Growth Factor-β Pathway Serves as a Primary Tumor Suppressor in CD8+ T Cell Tumorigenesis

Philip J. Lucas, Nicole E. McNeil, Eva Hilgenfeld et al. · Cancer Research · 2004 · 38 citations

Medicine, Genetics, Oncology +17