Giusy Tassone

Discovery of <b>ANT3310</b>, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and <i>Acinetobacter baumannii</i>

David T. Davies, Simon Leiris, Magdalena Zalacaín et al. · Journal of Medicinal Chemistry · 2020 · 34 citations · Full text

Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities

Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani et al. · Molecules · 2019 · 28 citations · Full text

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

Alice Legru, Federica Verdirosa, Jean‐François Hernandez et al. · European Journal of Medicinal Chemistry · 2021 · 26 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Re-sensitization Activity +13

Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02

Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2019 · 24 citations · Full text

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates

Alice Legru, Federica Verdirosa, Yen Vo‐Hoang et al. · Journal of Medicinal Chemistry · 2022 · 23 citations · Full text