Daichi Egawa

17-OxoDHA Is a PPARα/γ Dual Covalent Modifier and Agonist

Daichi Egawa, Toshimasa Itoh, Yui Akiyama et al. · ACS Chemical Biology · 2016 · 38 citations

Medicine, Biochemistry, Pharmacology +12

Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT

Naoki Nakao, Masaharu Ueno, Shota Sakai et al. · Communications Chemistry · 2019 · 35 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A Mixed Population of Antagonist and Agonist Binding Conformers in a Single Crystal Explains Partial Agonism against Vitamin D Receptor: Active Vitamin D Analogues with 22<i>R</i>-Alkyl Group

Yasuaki Anami, Toshimasa Itoh, Daichi Egawa et al. · Journal of Medicinal Chemistry · 2014 · 33 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif

Toshihiko Sugiki, Daichi Egawa, Keigo Kumagai et al. · Journal of Biological Chemistry · 2018 · 28 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics

Yasuaki Anami, Nobutaka Shimizu, Toru Ekimoto et al. · Journal of Medicinal Chemistry · 2016 · 24 citations

Life Sciences, Biochemistry, Molecular Biology +17