Gerhard Sperl

Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.

Gary A. Piazza, Alanna L. Kulchak Rahm, Mary F. Krutzsch et al. · PubMed · 1995 · 434 citations

Medicine, Oncology, Pharmacology +15

Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.

Gary A. Piazza, David S. Alberts, Lee J. Hixson et al. · PubMed · 1997 · 361 citations

Medicine, Oncology, Pharmacology +15

Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.

William J. Thompson, Gary A. Piazza, Han Li et al. · PubMed · 2000 · 305 citations

Life Sciences, Oncology, Pharmacology +16

Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines

Jin T. E. Lim, Gary A. Piazza, Edward K. Han et al. · Biochemical Pharmacology · 1999 · 210 citations

Medicine, Oncology, Pharmacology +8

Cyclic GMP-Dependent Protein Kinase Activation and Induction by Exisulind and CP461 in Colon Tumor Cells

Li Liu, Li Han, Tashandra Underwood et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 86 citations

Life Sciences, Oncology, Pharmacology +17