Christine M. Heske

Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

Choh Yeung, Anna E. Gibson, Sameer H. Issaq et al. · Cancer Research · 2019 · 130 citations · Full text

Medicine, Oncology, Pharmacology +14

Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma

Christine M. Heske, Mindy I. Davis, Joshua T. Baumgart et al. · Clinical Cancer Research · 2017 · 67 citations · Full text

Pharmacy, Oncology, Pharmacology +15

IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma

Xiaolin Wan, Choh Yeung, Christine M. Heske et al. · Neoplasia · 2015 · 47 citations · Full text

Medicine, Oncology, Pharmacology +17

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

Christine M. Heske, Arnulfo Mendoza, Leah D. Edessa et al. · Oncotarget · 2016 · 43 citations · Full text

Medicine, Pharmacology, Cancer Drug Toxicity Management +12

Survival outcomes of patients with localized <i>FOXO1</i> fusion‐positive rhabdomyosarcoma treated on recent clinical trials: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

Christine M. Heske, Yueh‐Yun Chi, Rajkumar Venkatramani et al. · Cancer · 2020 · 36 citations · Full text

Medicine, Oncology, Surgery +14