Patrick J Hu

Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation.

Jonathan Backer, Martin G. Myers, Steven E. Shoelson et al. · The EMBO Journal · 1992 · 1K citations · Full text

Molecular Pharmacology, Insulin Signaling, Molecular Physiology +14

IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.

Martin G. Myers, Jonathan Backer, Xiao‐Jian Sun et al. · Proceedings of the National Academy of Sciences · 1992 · 476 citations

Molecular Regulation, Irs-1 Activates, Molecular Biology +19

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

Ben Margolis, Patrick J Hu, Shulamit Katzav et al. · Nature · 1992 · 359 citations

Tyrosine Phosphorylation, Transcriptional Regulation, Viral Replication +11

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors.

Patrick J Hu, Benjamin Margolis, Edward Y. Skolnik et al. · Molecular and Cellular Biology · 1992 · 320 citations · Full text

Epidermal Growth Factor, Signal Transduction, Signaling Pathway +15

Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85.

Patrick J Hu, Anna Mondino, Edward Y. Skolnik et al. · Molecular and Cellular Biology · 1993 · 257 citations · Full text

Phosphatidylinositol 3-Kinase, Molecular Regulation, Human Pi 3-Kinase +17