Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications

Xiaoyu Chen, Ole Schulz-Trieglaff, Richard J. Shaw, +6

Bioinformatics

Strelka2: fast and accurate calling of germline and somatic variants

Sangtae Kim, Konrad Scheffler, Aaron L. Halpern, +8

Nature Methods

BiologyEngineeringSomatic VariantMedicineGenetics +11

Template-based protein structure modeling using the RaptorX web server

Morten Källberg, Haipeng Wang, Sheng Wang, +4

Nature Protocols

Raptorx Web ServerProtein FoldingMolecular BiologyProtein ModelingProtein Structure Prediction +4

A reference data set of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree

Michael A. Eberle, Epameinondas Fritzilas, Peter Krusche, +11

Genome Research

GeneticsGenomicsGenetic AnalysisMolecular EcologyGenome Analysis +18

Isaac: ultra-fast whole-genome secondary analysis on Illumina sequencing platforms

Come Raczy, Roman Petrovski, Christopher T. Saunders, +10

Bioinformatics

RaptorX server: A Resource for Template-Based Protein Structure Modeling

Morten Källberg, Gohar Margaryan, Sheng Wang, +2

Methods in molecular biology

Protein FoldingMolecular BiologyProtein BioinformaticsProtein ModelingProtein Structure Prediction +4

Fast and accurate genomic analyses using genome graphs

Goran Rakočević, Vladimir Semenyuk, Wan‐Ping Lee, +22

Nature Genetics

Functional GenomicsMolecular EcologyGeneticsComputational GenomicsComputational Biology +6

Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins

Ren Sheng, Yong Chen, Heon Yung Gee, +13

Nature Communications

Proteinlipid InteractionProtein FunctionSignal TransductionOxysterolAutophagy +6

Molecular Basis of the Potent Membrane-remodeling Activity of the Epsin 1 N-terminal Homology Domain

Youngdae Yoon, Jiansong Tong, Park Joo Lee, +8

Journal of Biological Chemistry

Genome-wide Functional Annotation of Dual-Specificity Protein- and Lipid-Binding Modules that Regulate Protein Interactions

Yong Chen, Ren Sheng, Morten Källberg, +8

Molecular Cell

BioinformaticsSystems BiologyInteractomicsGenome-wide Functional AnnotationMedicine +11