Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature

Knut Tore Lappegård, Dorte Christiansen, Anne Pharo, +13

Proceedings of the National Academy of Sciences

Chronic Inflammatory DiseasesImmunologyPathologyComplement Component C5Immunotherapy +16

Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis

Tom Sprong, Michael Fung, Anne Pharo, +6

Blood

Elimination of B-lymphoma cells from human bone marrow: model experiments using monodisperse magnetic particles coated with primary monoclonal antibodies.

Gunnar Kvalheim, Alexander Pihl, Kjell Nustad, +3

PubMed

Ib ProcedureHematological MalignancyCell TherapyLymphoid NeoplasiaMalignant Blood Disorder +11

Moderate hypothermia blunts the inflammatory response and reduces organ injury after acute haemorrhage

Yngvar Gundersen, Per Vaagenes, Anne Pharo, +2

Acta Anaesthesiologica Scandinavica

Properdin binding to complement activating surfaces depends on initial C3b deposition

M Harboe, Chris A. Johnson, Stig Nymo, +8

Proceedings of the National Academy of Sciences

CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in <i>Escherichia coli</i> sepsis in pigs

Ebbe Billmann Thorgersen, Bernt Christian Hellerud, Erik Waage Nielsen, +9

The FASEB Journal

Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood

Ole‐Lars Brekke, Dorte Christiansen, Hilde Fure, +4

Molecular Immunology

InflammationCytokineComplement SystemAutoimmune DiseaseAllergy +10

Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin

Espen Melum, Xiaojun Jiang, Kristi Baker, +17

Nature Immunology

InflammationAutoimmune DiseaseImmunologyPathologyImmunologic Mechanism +4

The artificial surface‐induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent

Knut Tore Lappegård, Grethe Bergseth, Johan Riesenfeld, +4

Journal of Biomedical Materials Research Part A

Early bedside detection of ischemia and rejection in liver transplants by microdialysis

Håkon Haugaa, Ebbe Billmann Thorgersen, Anne Pharo, +9

Liver Transplantation