Yoko Nagaya

Utility of Cerebrospinal Fluid Drug Concentration as a Surrogate for Unbound Brain Concentration in Nonhuman Primates

Yoko Nagaya, Yoshitane Nozaki, Kazumasa Kobayashi et al. · Drug Metabolism and Pharmacokinetics · 2014 · 36 citations

Pharmacodynamic and pharmacokinetic interactions of perampanel and other antiepileptic drugs in a rat amygdala kindling model

Ting Wu, Yoko Nagaya, Takahisa Hanada · Seizure · 2014 · 31 citations · Full text

Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(−/−) rats

Yoko Nagaya, Yoshitane Nozaki, Osamu Takenaka et al. · Drug Metabolism and Pharmacokinetics · 2015 · 15 citations · Full text

Csf Values, Interstitial Fluid Concentration, Ccsf-to-cisf Gradient +19

Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates

Yoko Nagaya, Kazuhide Katayama, Hiroyuki Kusuhara et al. · Drug Metabolism and Disposition · 2020 · 14 citations · Full text

Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data

Kayoko Kanamitsu, Yoshitane Nozaki, Yoko Nagaya et al. · Drug Metabolism and Pharmacokinetics · 2016 · 11 citations

Allergy, Neurophysiology, Medicine +11