23:T543,A new lignan (T4) and three known lignans (T1, T2, and T3) were isolated from the methanol extract of the roots of Phryma leptostachya using bioassay-guided method, and their structures were identified as phrymarolin I (T1), II (T2), haedoxan A (T3), and methyl 4-((6a-acetoxy-4-(6-methoxybenzo[d][1,3]dioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)oxy)-1-hydroxy-2,2-dimethoxy-5-oxocyclopent-3-ene-1-carboxylate (T4) byNMR and ESI-MS spectral data. Bioassay results revealed that haedoxan A exhibited remarkably high insecticidal activity against Mythimna separata with a stomach toxicity LC₅₀ value of 17.06 mg/L and a topical toxicity LC₅₀ value of 1123.14 mg/L at 24 h, respectively. Phrymarolin I and compound T4 also showed some stomach toxicity against M. separata with KD₅₀ values of 3450.21 mg/L at 4 h and 2807.10 mg/L at 8 h, respectively. In addition, phrymarolin I and haedoxan A exhibited some stomach toxicity against Plutella xylostella with an LC₅₀ value of 1432.05 and 857.28 mg/L at 48 h, respectively. In conclusion, this study demonstrated that lignans from P. leptostachya are promising as a novel class of insecticides or insecticide lead compounds for developing botanical pesticides.24:T46a,Abstract Spintronic devices can realize multi‐state storage and be used to simulate artificial synapses or artificial neurons, which makes them have promising application prospect in the field of artificial neural networks (ANN). This work investigates the current‐induced magnetization reversal in stacked (Ta/CoFeB/MgO) N structures and their application in ANN. It is demonstrated that the complete current‐induced magnetization reversal with large intermediate transition region can be achieved in the sample with N = 2. The magneto‐optical Kerr microscope imaging shows that the large transition region for the sample is ascribed to the “layer‐by‐layer” reversal, owing to the difference of the coercivity of two CoFeB layers. In addition, the simulation of artificial synapses and artificial neurons function based on current‐induced magnetization reversal in the sample is also demonstrated. These results substantiate the stacked (Ta/CoFeB/MgO) N structures as a promising platform for realizing the multi‐level state and artificial synapses function, and its potential application in the field of ANN.25:T56f,

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1	Engineering	2	2	47
2	Health Sciences	1	1	32
3	Medicine	1	1	29
4	Natural Sciences	1	1	18
5	Applied Physics	1	1	18

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