Deborah L. Croteau

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

Evandro Fei Fang, Yujun Hou, Konstantinos Palikaras et al. · Nature Neuroscience · 2019 · 1.6K citations · Full text

Mitophagy, Neurodegenerative Diseases, Alzheimer's Disease +11

Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction

Evandro Fei Fang, Morten Scheibye‐Knudsen, Lear E. Brace et al. · Cell · 2014 · 688 citations · Full text

Cell Autophagy, Mitophagy, Natural Sciences +12

NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

Evandro Fei Fang, Henok Kassahun, Deborah L. Croteau et al. · Cell Metabolism · 2016 · 560 citations · Full text

Lifespan Extension, Genome Instability, Medicine +10

NAD ⁺ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING

Yujun Hou, Yong Wei, Sofie Lautrup et al. · Proceedings of the National Academy of Sciences · 2021 · 465 citations · Full text

NAD ⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Yujun Hou, Sofie Lautrup, Stephanie A. Cordonnier et al. · Proceedings of the National Academy of Sciences · 2018 · 444 citations · Full text