Stephen T. Safrany

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

David Komander, Alison Fairservice, Mária Deák et al. · The EMBO Journal · 2004 · 178 citations · Full text

Proteinlipid Interaction, Protein Function, Signal Transduction +11

A novel context for the `MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

Stephen T. Safrany · The EMBO Journal · 1998 · 168 citations · Full text

Protein Function, Signal Transduction, Cell Integrity +11

Small Molecule Antagonists of the σ-1 Receptor Cause Selective Release of the Death Program in Tumor and Self-Reliant Cells and Inhibit Tumor Growth <b> <i>in Vitro</i> </b> and <b> <i>in Vivo</i> </b>

Barbara A. Spruce, Lorna Campbell, N. McTavish et al. · Cancer Research · 2004 · 165 citations

The Diadenosine Hexaphosphate Hydrolases fromSchizosaccharomyces pombe and Saccharomyces cerevisiae Are Homologues of the Human Diphosphoinositol Polyphosphate Phosphohydrolase

Stephen T. Safrany, Stephen W. Ingram, Jared Cartwright et al. · Journal of Biological Chemistry · 1999 · 146 citations · Full text

Differential redox regulation within the PTP superfamily

Sarah H. Ross, Yvonne Lindsay, Stephen T. Safrany et al. · Cellular Signalling · 2007 · 101 citations

Reductive Stress, Redox Signaling, Signal Transduction +10