Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA

Zhikuan Zhang, Umeharu Ohto, Takuma Shibata, +8

Immunity

Toll-like Receptor 7Toll-like ReceptorsDual ReceptorSingle-stranded RnaNatural Sciences +6

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Umeharu Ohto, Takuma Shibata, Hiromi Tanji, +5

Nature

Toll-like ReceptorsMolecular ImmunologySignal TransductionToll-like Receptor 9Inhibitory Dna Recognition +7

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Yasuaki Kabe, Takanori Nakane, Ikko Koike, +18

Nature Communications

Structure of IZUMO1–JUNO reveals sperm–oocyte recognition during mammalian fertilization

Umeharu Ohto, Hanako Ishida, Elena Krayukhina, +3

Nature

Developmental BiologyFertilityGeneticsFertilisationReproductive Biology +3

Effects of Syringe Material and Silicone Oil Lubrication on the Stability of Pharmaceutical Proteins

Elena Krayukhina, Kouhei Tsumoto, Susumu Uchiyama, +1

Journal of Pharmaceutical Sciences

Biofunctional MaterialProtein ChemistrySyringe MaterialEngineeringProtein Nanoparticles +13

A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

Huaying Zhao, Rodolfo Ghirlando, Carlos Alfonso, +116

PLoS ONE

EngineeringCalibration AccuracyMeasurementDifferential Scanning CalorimetryBiomedical Engineering +23

An Assessment of the Ability of Submicron- and Micron-Size Silicone Oil Droplets in Dropped Prefillable Syringes to Invoke Early- and Late-Stage Immune Responses

Elena Krayukhina, Masami Yokoyama, Kayoko Hayashihara, +5

Journal of Pharmaceutical Sciences

Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains

Eriko Nango, Shuji Akiyama, Saori Maki-Yonekura, +14

Scientific Reports

Automatic Identification of the Stress Sources of Protein Aggregates Using Flow Imaging Microscopy Images

Arni Gambe-Gilbuena, Yuriko Shibano, Elena Krayukhina, +2

Journal of Pharmaceutical Sciences

EngineeringMicroscope Image ProcessingMicroscopyStress SourcesMedicine +11

Quantitative Laser Diffraction for Quantification of Protein Aggregates: Comparison With Resonant Mass Measurement, Nanoparticle Tracking Analysis, Flow Imaging, and Light Obscuration

Saki Yoneda, Bertram Niederleitner, Michael Wiggenhorn, +4

Journal of Pharmaceutical Sciences

Quantitative Laser DiffractionEngineeringMicroscopyBiological Mass SpectrometryBiomedical Engineering +22