Lei Jia

Protein asparagine deamidation prediction based on structures with machine learning methods

Lei Jia, Yaxiong Sun · PLoS ONE · 2017 · 68 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +14

Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies

Marissa Mock, Alex W. Jacobitz, Christopher J. Langmead et al. · mAbs · 2023 · 28 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Developing a Naïve Bayesian Classification Model with PI3Kγ structural features for virtual screening against PI3Kγ: Combining molecular docking and pharmacophore based on multiple PI3Kγ conformations

Yingmin Jiang, Wendian Xiong, Lei Jia et al. · European Journal of Medicinal Chemistry · 2022 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Evaluation of the anti-inflammatory effects of PI3Kδ/γ inhibitors for treating acute lung injury

Wendian Xiong, Lei Jia, Yanfei Cai et al. · Immunobiology · 2023 · 17 citations

Medicine, Immunology, Pharmacology +15

Exploring PI3Kγ binding preference with Eganelisib, Duvelisib, and Idelalisib via energetic, pharmacophore and dissociation pathway analyses

Lei Jia, Lingling Wang, Yingmin Jiang et al. · Computers in Biology and Medicine · 2022 · 12 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12