Valerie R. Wiersma

CD20-selective inhibition of CD47-SIRPα “don't eat me” signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab

Peter E. van Bommel, Yuan He, Ilona Schepel et al. · OncoImmunology · 2017 · 67 citations · Full text

Life Sciences, Immunology, Oncology +17

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux

Valerie R. Wiersma, Marco de Bruyn, Yunwei Wei et al. · Autophagy · 2015 · 54 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Galectin-9 Activates and Expands Human T-Helper 1 Cells

Marloes J.M. Gooden, Valerie R. Wiersma, Douwe F. Samplonius et al. · PLoS ONE · 2013 · 54 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction

Djoke Hendriks, Yuan He, Iris Koopmans et al. · OncoImmunology · 2016 · 47 citations · Full text

Life Sciences, Immunology, Oncology +17

Galectin-9 Is a Possible Promoter of Immunopathology in Rheumatoid Arthritis by Activation of Peptidyl Arginine Deiminase 4 (PAD-4) in Granulocytes

Valerie R. Wiersma, Alex Clarke, Simon D. Pouwels et al. · International Journal of Molecular Sciences · 2019 · 38 citations · Full text

Medicine, Immunology, Pathology +14