Valerie R. Wiersma

CD20-selective inhibition of CD47-SIRPα “don't eat me” signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab

Peter E. van Bommel, Yuan He, Ilona Schepel et al. · OncoImmunology · 2017 · 65 citations · Full text

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux

Valerie R. Wiersma, Marco de Bruyn, Yunwei Wei et al. · Autophagy · 2015 · 54 citations · Full text

Mitophagy, Immunology, Cell Death +16

Galectin-9 Activates and Expands Human T-Helper 1 Cells

Marloes J.M. Gooden, Valerie R. Wiersma, Douwe F. Samplonius et al. · PLoS ONE · 2013 · 54 citations · Full text

Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction

Djoke Hendriks, Yuan He, Iris Koopmans et al. · OncoImmunology · 2016 · 46 citations · Full text

Apoptosis, Immunology, Pd-l1 Checkpoint Inhibition +18

Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity

Marloes J.M. Gooden, Valerie R. Wiersma, Annemarie Boerma et al. · British Journal of Cancer · 2014 · 37 citations · Full text