Brian G. Kral

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

Xihao Li, Zilin Li, Hufeng Zhou et al. · Nature Genetics · 2020 · 290 citations · Full text

Life Sciences, Bioinformatics, Genetics +17

A Bivariate Genome-Wide Approach to Metabolic Syndrome

Aldi T. Kraja, Dhananjay Vaidya, James S. Pankow et al. · Diabetes · 2011 · 255 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Beyond Low-Density Lipoprotein Cholesterol

James O. Mudd, Barry A. Borlaug, Peter V. Johnston et al. · Journal of the American College of Cardiology · 2007 · 135 citations

Life Sciences, Nutritional Sciences, Lipid Biochemistry +5

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

Michael D. Kessler, Douglas P. Loesch, James A. Perry et al. · Proceedings of the National Academy of Sciences · 2020 · 112 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

Zilin Li, Xihao Li, Hufeng Zhou et al. · Nature Methods · 2022 · 109 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14