Paul J. Grippo

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

Carmen Guerra, Alberto J. Schuhmacher, Marta Cañamero et al. · Cancer Cell · 2007 · 1.2K citations · Full text

Chronic Pancreatitis, Pancreatic Cancer, Oncogenic Agent +10

Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice.

Paul J. Grippo, Patrick S. Nowlin, Michael J. Demeure et al. · PubMed · 2003 · 212 citations

Knockout Mouse, Cancer Research, Developmental Biology +15

The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice.

Felix H. Brembeck, Franz S. Schreiber, Thérèse B. Deramaudt et al. · PubMed · 2003 · 193 citations

Pancreatic Cancer, Oncogenic Agent, Cell Signaling +14

TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

Daniel R. Principe, Brian DeCant, Emman Mascariñas et al. · Cancer Research · 2016 · 188 citations · Full text

Immunology, Immune Regulation, Pathology +21

Three-Dimensional Collagen I Promotes Gemcitabine Resistance in Pancreatic Cancer through MT1-MMP–Mediated Expression of HMGA2

Surabhi Dangi‐Garimella, Seth B. Krantz, Morgan R. Barron et al. · Cancer Research · 2010 · 179 citations · Full text