S.P. Stokes

Synthesis of Ynone Trifluoroborates toward Functionalized Pyrazoles

James D. Kirkham, Steven J. Edeson, S.P. Stokes et al. · Organic Letters · 2012 · 119 citations

Pyrazole Trifluoroborate Salts, Functionalized Pyrazoles, Propargylic Alcohols +5

Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist

James S. Scott, Amber Balazs, Bernard Barlaam et al. · Journal of Medicinal Chemistry · 2020 · 109 citations · Full text

Will they co-crystallize?

Jerome G. P. Wicker, Lorraine M. Crowley, Oliver Robshaw et al. · CrystEngComm · 2017 · 102 citations · Full text

Engineering, Biomolecular Structure Prediction, Molecular Biology +16

Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3<i>R</i>)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-<i>b</i>]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153)

Robert H. Bradbury, Rowena Callis, Gregory R. Carr et al. · Journal of Medicinal Chemistry · 2016 · 85 citations · Full text

Pharmaceutical Science, Chemoprevention Strategy, Organic Chemistry +21

Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization

Nicholas G. Davies, Helen Browne, Ben Davis et al. · Bioorganic & Medicinal Chemistry · 2012 · 45 citations · Full text

Drug Target, Medicine, Natural Sciences +10