Ben Davis

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-<i>d</i>]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

Paul A. Brough, Xavier Barril, Jenifer Borgognoni et al. · Journal of Medicinal Chemistry · 2009 · 173 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Rational Design of Inhibitors of HIV-1 TAR RNA through the Stabilisation of Electrostatic “Hot Spots”

Ben Davis, Mohammad Afshar, Gabriele Varani et al. · Journal of Molecular Biology · 2004 · 156 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Learning from our mistakes: The ‘unknown knowns’ in fragment screening

Ben Davis, Daniel A. Erlanson · Bioorganic & Medicinal Chemistry Letters · 2013 · 145 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Structure-based Drug Design Targeting an Inactive RNA Conformation: Exploiting the Flexibility of HIV-1 TAR RNA

Alastair I.H. Murchie, Ben Davis, Catherine Isel et al. · Journal of Molecular Biology · 2003 · 143 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Perturbed pKA-values in the Denatured States of Proteins

Yee‐Joo Tan, Mikael Oliveberg, Ben Davis et al. · Journal of Molecular Biology · 1995 · 133 citations

Life Sciences, Biochemistry, Biophysics +12