Ben Davis

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-<i>d</i>]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

Paul A. Brough, Xavier Barril, Jenifer Borgognoni et al. · Journal of Medicinal Chemistry · 2009 · 173 citations · Full text

Rational Design of Inhibitors of HIV-1 TAR RNA through the Stabilisation of Electrostatic “Hot Spots”

Ben Davis, Mohammad Afshar, Gabriele Varani et al. · Journal of Molecular Biology · 2004 · 152 citations

Biochemistry, Rational Design, Natural Sciences +9

Learning from our mistakes: The ‘unknown knowns’ in fragment screening

Ben Davis, Daniel A. Erlanson · Bioorganic & Medicinal Chemistry Letters · 2013 · 145 citations · Full text

Drug Target, Hit Identification, Fragment-based Lead Discovery +24

Structure-based Drug Design Targeting an Inactive RNA Conformation: Exploiting the Flexibility of HIV-1 TAR RNA

Alastair I.H. Murchie, Ben Davis, Catherine Isel et al. · Journal of Molecular Biology · 2003 · 140 citations

Engineering, Protein Folding, Rna Structure Prediction +12

Perturbed pKA-values in the Denatured States of Proteins

Yee‐Joo Tan, Mikael Oliveberg, Ben Davis et al. · Journal of Molecular Biology · 1995 · 132 citations

Protein Chemistry, Protein Function, Biochemistry +5