Lidia Carotenuto

KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism

Francesco Miceli, Charissa Millevert, Maria Virginia Soldovieri et al. · EBioMedicine · 2022 · 42 citations · Full text

Medicine, Genetics, Pharmacology +17

Gain of function due to increased opening probability by two <i>KCNQ5</i> pore variants causing developmental and epileptic encephalopathy

Mario Nappi, Vincenzo Barrese, Lidia Carotenuto et al. · Proceedings of the National Academy of Sciences · 2022 · 38 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity

Simona Musella, Lidia Carotenuto, Nunzio Iraci et al. · Journal of Medicinal Chemistry · 2022 · 37 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

<i>In Silico</i> Assisted Identification, Synthesis, and <i>In Vitro</i> Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel

Nunzio Iraci, Lidia Carotenuto, Tania Ciaglia et al. · Journal of Medicinal Chemistry · 2024 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate

Francesco Miceli, Lidia Carotenuto, Vincenzo Barrese et al. · Frontiers in Physiology · 2020 · 14 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17