Resolving medulloblastoma cellular architecture by single-cell genomics

Volker Hovestadt, Kyle Smith, Laure Bihannic, +48

Nature

Tumor HeterogeneityMedicineSingle Cell SequencingSingle-cell BiologySingle-cell Genomics +3

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Peer W. F. Karmaus, Xiang Chen, Seon Ah Lim, +14

Nature

Lineage PlasticityCell LineageDevelopmental BiologyMedicineStem Cell Research +7

A Single-Cell Transcriptional Atlas of the Developing Murine Cerebellum

Robert Carter, Laure Bihannic, Celeste Rosencrance, +7

Current Biology

Genetic Risk for Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer

Zhaoming Wang, Carmen L. Wilson, John Easton, +46

Journal of Clinical Oncology

Distinct SnsCancer PathologyGeneticsGenetic EpidemiologyPathology +25

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo

André Bortolini Silveira, Lawryn H. Kasper, Yiping Fan, +23

Acta Neuropathologica

Neuro-oncologyGliomaCell ProliferationHigh-grade GliomasRadiation Oncology +6

Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment

Celeste Rosencrance, Haneen Ammouri, Qi Yu, +4

Molecular Cell

ChromatinGenome InstabilityChromatin StructureChromatin RemodelingNatural Sciences +10

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

Kai Yang, Daniel Bastardo Blanco, Xiang Chen, +12

Science Immunology

High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor

Tetsuji Yamashita, Fei Zheng, David Finkelstein, +7

PLoS Genetics

Conversion EfficiencyHigh-resolution Transcriptional DissectionTranscriptional RegulationSingle Cell SequencingHc Conversion Efficiency +15

Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data

Changde Cheng, John Easton, Celeste Rosencrance, +7

Nucleic Acids Research

EngineeringGeneticsTranscriptomics TechnologyGenomicsGene Expression Profiling +22

UBR7 acts as a histone chaperone for post‐nucleosomal histone H3

Ann Hogan, Kizhakke Mattada Sathyan, Alexander B. Willis, +14

The EMBO Journal

Histone ModificationsChromatinChromatin StructureChromatin RemodelingNatural Sciences +8