Hwee Ching Ang

Structural basis for understanding oncogenic p53 mutations and designing rescue drugs

Andreas C. Joerger, Hwee Ching Ang, Alan R. Fersht · Proceedings of the National Academy of Sciences · 2006 · 336 citations · Full text

Engineering, Molecular Biology, Tumor Biology +20

Structures of p53 Cancer Mutants and Mechanism of Rescue by Second-site Suppressor Mutations

Andreas C. Joerger, Hwee Ching Ang, Dmitry B. Veprintsev et al. · Journal of Biological Chemistry · 2005 · 182 citations · Full text

Mutant P53, P53 Cancer Mutants, Genome Instability +14

Solution structure of p53 core domain: Structural basis for its instability

José Manuel Pérez‐Cañadillas, Henning Tidow, Stefan M.V. Freund et al. · Proceedings of the National Academy of Sciences · 2006 · 175 citations · Full text

Crystal Structure, Structural Bioinformatics, Biomolecular Structure Prediction +17

Effects of Common Cancer Mutations on Stability and DNA Binding of Full-length p53 Compared with Isolated Core Domains

Hwee Ching Ang, Andreas C. Joerger, Sebastian Mayer et al. · Journal of Biological Chemistry · 2006 · 146 citations · Full text

Molecular Biology, Cancer Biology, Protein Folding +20

Correlation of Levels of Folded Recombinant p53 in Escherichia coli with Thermodynamic Stability in Vitro

Sebastian Mayer, Stefan Rüdiger, Hwee Ching Ang et al. · Journal of Molecular Biology · 2007 · 91 citations

Folded Recombinant P53, Protein Folding, Bioenergetics +7