CD4+CD25+ T Cells Regulate Virus-specific Primary and Memory CD8+ T Cell Responses

Susmit Suvas, Uday Kumaraguru, Christopher D. Pack, +2

The Journal of Experimental Medicine

T-regulatory CellImmunologyAntigen ProcessingCd4 T Cell ResponsesImmunotherapy +15

Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection

Christopher S. Sullivan, Chang K. Sung, Christopher D. Pack, +4

Virology

Experimental InfectionPathogenesisPathologyVirologyMurine Polyomavirus +7

Metformin reduces PD-L1 on tumor cells and enhances the anti-tumor immune response generated by vaccine immunotherapy

Luis E. Muñoz, Lei Huang, Ramireddy Bommireddy, +9

Journal for ImmunoTherapy of Cancer

The Antiviral CD8+ T Cell Response Is Differentially Dependent on CD4+ T Cell Help Over the Course of Persistent Infection

Christopher C. Kemball, Christopher D. Pack, Heath Guay, +4

The Journal of Immunology

Neonatal Exposure to a Self-Peptide–Immunoglobulin Chimera Circumvents the Use of Adjuvant and Confers Resistance to Autoimmune Disease by a Novel Mechanism Involving Interleukin 4 Lymph Node Deviation and Interferon γ–mediated Splenic Anergy

Booki Min, Kevin L. Legge, Christopher D. Pack, +1

The Journal of Experimental Medicine

An MHC class Ib–restricted CD8 T cell response confers antiviral immunity

Phillip A. Swanson, Christopher D. Pack, Annette Hadley, +4

The Journal of Experimental Medicine

Plasma membrane vesicles decorated with glycolipid-anchored antigens and adjuvants via protein transfer as an antigen delivery platform for inhibition of tumor growth

Jaina M. Patel, Vincent F. Vartabedian, Erica N. Bozeman, +7

Biomaterials

Plasma Membrane VesiclesTumor GrowthImmunologyProtein TransferTherapeutic Vaccine +6

Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune checkpoint resistant murine triple-negative breast cancer

Christopher D. Pack, Ramireddy Bommireddy, Luis E. Muñoz, +9

Human Vaccines & Immunotherapeutics

Gamma Interferon Controls Mouse Polyomavirus Infection<i>In Vivo</i>

Jarad Wilson, Eugene Lin, Christopher D. Pack, +9

Journal of Virology

Heat-shock protein 70 acts as an effective adjuvant in neonatal mice and confers protection against challenge with Herpes Simplex Virus

Christopher D. Pack, Udayasankar Kumaraguru, Susmit Suvas, +1

Vaccine

VaccinationViral PathogenesisImmunologyHerpes Simplex VirusVirology +7