Yuancai Xiang

The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression

Yiguo Zhang, Shaojun Li, Yuancai Xiang et al. · Scientific Reports · 2015 · 63 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells

Yonggang Ren, Lu Qiu, Feng-Lin Lu et al. · Scientific Reports · 2016 · 55 citations · Full text

Medicine, Molecular Biology, Oncology +15

Mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits

Yuancai Xiang, Meng Wang, Shaofan Hu et al. · Toxicology and Applied Pharmacology · 2018 · 47 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Compound C induces protective autophagy in human cholangiocarcinoma cells via Akt/mTOR‐independent pathway

Xiaofang Zhao, Guosong Luo, Ying Cheng et al. · Journal of Cellular Biochemistry · 2018 · 32 citations

Life Sciences, Cancer Biology, Cell Biology +17

The C-Terminal Domain of Nrf1 Negatively Regulates the Full-Length CNC-bZIP Factor and Its Shorter Isoform LCR-F1/Nrf1β; Both Are Also Inhibited by the Small Dominant-Negative Nrf1γ/δ Isoforms that Down-Regulate ARE-Battery Gene Expression

Yiguo Zhang, Lu Qiu, Shaojun Li et al. · PLoS ONE · 2014 · 27 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14