James H. Holms

3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives: inhibitors of immune complex induced inflammation

Fortuna Haviv, James D. Ratajczyk, Robert W. DeNet et al. · Journal of Medicinal Chemistry · 1988 · 164 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Phenoxyphenyl Sulfone<i>N</i>-Formylhydroxylamines (Retrohydroxamates) as Potent, Selective, Orally Bioavailable Matrix Metalloproteinase Inhibitors

Carol K. Wada, James H. Holms, Michael L. Curtin et al. · Journal of Medicinal Chemistry · 2001 · 103 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Hydroxamic acid inhibitors of 5-lipoxygenase

James B. Summers, Hormoz Mazdiyasni, James H. Holms et al. · Journal of Medicinal Chemistry · 1987 · 86 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

α-Keto amides as inhibitors of histone deacetylase

Carol K. Wada, Robin R. Frey, Zhiqin Ji et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 81 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +10

Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors

Le Wang, John K. Pratt, Todd Soltwedel et al. · Journal of Medicinal Chemistry · 2017 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17