John R. James

Biophysical mechanism of T-cell receptor triggering in a reconstituted system

John R. James, Ronald D. Vale · Nature · 2012 · 334 citations

Signal Transduction, Adaptive Immune System, T-regulatory Cell +10

A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer

John R. James, Marta I. Oliveira, Alexandre M. Carmo et al. · Nature Methods · 2006 · 314 citations

Rigorous Experimental Framework, Biomolecular Tool, Biomolecular Analysis +4

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing

Ji Li, Nicola J. Stagg, Jennifer Johnston et al. · Cancer Cell · 2017 · 289 citations · Full text

Synapse Formation, Immunology, Immunoediting +16

Crystal structure of a soluble CD28-Fab complex

Edward J. Evans, Robert Esnouf, Raquel Manso-Sancho et al. · Nature Immunology · 2005 · 173 citations

Crystal Structure, Structure Elucidation, Molecular Biology +3

Selective, rapid and optically switchable regulation of protein function in live mammalian cells

Yu‐Hsuan Tsai, Sebastian Essig, John R. James et al. · Nature Chemistry · 2015 · 156 citations · Full text

Protein Function, Signal Transduction, Molecular Regulation +11